X0202 4 2007-02-09 0 0001157601 SYNTA PHARMACEUTICALS CORP SNTA 0001325713 Kovner Bruce C/O CAXTON ASSOCIATES 500 PARK AVENUE NEW YORK NY 10022 1 0 1 0 Common Stock 2006-11-17 4 A 0 2857 0 A 87954 D Common Stock 2007-02-09 4 C 0 23648 A 111602 D Common Stock 2007-02-09 4 P 0 720000 10 A 831602 D Common Stock 2007-02-09 4 C 0 1690646 A 7761716 I By CxSynta LLC Series A Convertible Preferred Stock 2007-02-09 4 C 0 30131 0 D Common Stock 23648 0 D Series A Convertible Preferred Stock 2007-02-09 4 C 0 2154105 0 D Common Stock 1690646 0 I By CxSynta LLC Reflects a 1-for-4 reverse stock split effected on February 2, 2007 in connection with the Issuer's initial public offering, pursuant to which the number of shares of Common Stock was divided by 4. Upon the closing of the Issuer's initial public offering on February 9, 2007, each share of Series A Convertible Preferred Stock, plus accrued dividends, converted into approximately .7848 shares of Common Stock. These shares are owned directly by CxSynta LLC and indirectly by the Reporting Person as Chairman of Caxton Corporation, the managing member of CxSynta LLC. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. N/A. /s/ Scott B. Bernstein, Attorney-in-Fact 2007-02-13