X0306 4 2015-09-30 0 0001157601 SYNTA PHARMACEUTICALS CORP SNTA 0001325713 Kovner Bruce C/O CAXTON CORPORATION 731 ALEXANDER ROAD, BLDG. 2 PRINCETON NJ 08540 1 0 1 0 Common Stock 2015-09-30 4 J 0 120854 A 15399464 I By KFO Holdings LLC Common Stock 2015-09-30 4 J 0 120854 D 0 I By Kovner 2012-D Synta Investment Trust Common Stock 2015-09-30 4 J 0 4000000 A 4000000 I By Kovner 2015-A Investment Trust Common Stock 2015-09-30 4 J 0 4000000 D 11399464 I By KFO Holdings LLC Common Stock 3092677 D Common Stock 2279146 I By Wife Common Stock 5460000 I By OB Select Opportunities, LLC Common Stock 7761716 I By CxSynta LLC Common Stock 3100000 I By Kovner 2012 Family Trust B Reflects the transfer of 120,854 shares from the Kovner 2012-D Synta Investment Trust to KFO Holdings LLC. Reflects the transfer of 4,000,000 shares from KFO Holdings LLC to the Kovner 2015-A Investment Trust. These shares are owned directly by KFO Holdings LLC and indirectly by the Reporting Person as chairman and sole shareholder of Caxton Corporation, the manager of KFO Holdings LLC. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These securities are owned by the wife of the Reporting Person. These shares are owned directly by OB Select Opportunities, LLC and indirectly by the Reporting Person as chairman and sole shareholder of Caxton Corporation, the manager of OB Select Opportunities, LLC. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. These shares are owned directly by CxSynta LLC and indirectly by the Reporting Person as chairman and sole shareholder of Caxton Corporation, the managing member of CxSynta LLC. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. /s/Heath N. Weisberg, Attorney-In-Fact 2015-10-02