X0306 4 2012-07-25 0 0001157601 SYNTA PHARMACEUTICALS CORP SNTA 0001325712 Gollust Keith R C/O SYNTA PHARMACEUTICALS CORP. 45 HARTWELL AVENUE LEXINGTON MA 02421 1 0 0 0 Common Stock 2012-07-25 4 A 0 770416 6.49 A 2598383 I By Wyandanch Partners, L.P. Common Stock 202005 D The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, if any, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. /s/ Ann Margaret Eames, Attorney-in-Fact 2012-07-27