X0306 4 2019-09-06 0 0000917520 INTEGRA LIFESCIENCES HOLDINGS CORP IART 0001323134 Arduini Peter J 311 C ENTERPRISE DRIVE PLAINSBORO NJ 08536 1 1 0 0 President & CEO Common Stock 2019-09-06 4 M 0 250000 13.89 A 433017 D Common Stock 2019-09-06 4 S 0 250000 60.5486 D 183017 D Non-Qualified Stock Option (right to buy) 13.89 2019-09-06 4 M 0 250000 0.00 D 2020-03-01 Common Stock 250000 115864 D The transaction reported in this Form 4 was affected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person. The price shown above represents the weighted average price of the shares sold. The range of sale prices was $60.545 to $60.705. One-third of the stock options vested on the first anniversary of the grant date which is March 1, 2012 and thereafter with respect to the remaining two-thirds which vested in monthly installments through the 3rd anniversary of the grant date. /s/ Eric Schwartz; Attorney-in-Fact 2019-09-10