Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue:
Revenue	$ 8,206	$ 2,428	$ 15,038	$ 4,394
Cost and operating expenses:
Cost of product revenue	776		1,010
Research and development	22,888	20,894	44,791	40,837
Selling, general and administrative	21,600	16,940	38,455	32,213
Other operating expense, net	145	(2,374)	7,543	4,154
Total cost and operating expenses	45,409	35,460	91,799	77,204
Operating loss	(37,203)	(33,032)	(76,761)	(72,810)
Other loss:
Interest expense, net	(2,746)	(3,389)	(5,622)	(7,344)
Net loss	$ (39,949)	$ (36,421)	$ (82,383)	$ (80,154)
Net loss per share attributable to holders of common stock
Net loss per common share - Basic (in dollars per share)	$ (2.04)	$ (1.90)	$ (4.23)	$ (4.18)
Net loss per common share - Diluted (in dollars per share)	$ (2.04)	$ (1.90)	$ (4.23)	$ (4.18)
Weighted-average common shares used to compute basic and diluted net loss per common share
Basic (in shares)	19,585,164	19,200,747	19,482,943	19,196,798
Diluted (in shares)	19,585,164	19,200,747	19,482,943	19,196,798
Product
Revenue:
Revenue	$ 5,891	$ 0	$ 10,547	$ 0
Royalty
Revenue:
Revenue	$ 2,315	$ 2,428	$ 4,491	$ 4,394