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Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
12 Months Ended 94 Months Ended
Sep. 30, 2011
Sep. 30, 2010
Sep. 30, 2009
Sep. 30, 2011
Cash flows from operating activities:        
Net loss $ (10,592) $ (38,290) $ (43,270) $ (170,286)
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation and amortization 938 991 877 4,078
Founder's compensation contributed to capital       271
Share-based compensation for employees and directors 4,964 5,628 4,970 25,796
Share-based compensation for non-employees (44) (7) 94 2,274
Loss on settlement of debt       627
Write-off of capitalized patent expense       208
Write-off of loan to related party       41
Adjustment to fair value of common stock warrant liability (12,611) 1,254   (11,357)
(Increase) decrease in:        
Prepaid expenses and other assets (41) 117 768 (406)
Income taxes receivable 81 636 1,236 (35)
Other receivable 10 (11)   (1)
Increase (decrease) in:        
Accounts payable (1,767) 982 194 222
Income tax payable 58 (120) (847) 103
Accrued expenses and other liabilities 753 (5,561) 715 3,325
Total adjustments (7,659) 3,909 8,007 25,146
Net cash used in operating activities (18,251) (34,381) (35,263) (145,140)
Cash flows from investing activities:        
Purchase of property and equipment (189) (292) (637) (6,290)
Purchase of marketable securities   (6,000)   (31,614)
Sale of marketable securities 6,000   25,614 31,614
Capitalized intellectual properties       (298)
Loan to related party       (41)
Net cash provided by (used in) investing activities 5,811 (6,292) 24,977 (6,629)
Cash flows from financing activities:        
Restricted cash 90 (150)   (60)
Options exercised   68 25 1,000
Warrants exercised 50     585
Deferred public offering costs       (1,458)
Stockholder contribution       1,660
Net proceeds from employee stock purchase plan 118 325 170 794
Net proceeds from sale of common stock 25,276 8,712   161,018
Proceeds from bridge financing       2,575
Net cash provided by financing activities 28,219 8,955 195 190,470
Net increase (decrease) in cash and cash equivalents 15,779 (31,718) (10,091) 38,701
Cash and cash equivalents, beginning of period 22,922 54,640 64,731  
Cash and cash equivalents, end of period 38,701 22,922 54,640 38,701
Cash paid for interest and income taxes was:        
Interest       9
Income taxes   60 111 306
Non-cash financing and investing activities:        
Warrants issued in connection with registered direct offering 9,438 2,915   12,353
Settlement of debt with Series B preferred stock       3,202
Accrued expenses settled with Series B preferred stock       150
Deemed dividend - warrants       4,457
Accretion of fair value of beneficial charge on preferred stock       603
Conversion of convertible preferred stock to common stock       68
Series A Preferred stock
       
Cash flows from financing activities:        
Net proceeds from sale of Series A preferred stock 2005       2,466
Net proceeds from sale of Series A preferred stock 2011 2,685     2,685
Series B Preferred stock
       
Cash flows from financing activities:        
Net proceeds from sale of Series A preferred stock 2005       $ 19,205