<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2018-01-22</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001320760</issuerCik>
        <issuerName>TSS, Inc.</issuerName>
        <issuerTradingSymbol>TSSI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001729129</rptOwnerCik>
            <rptOwnerName>Brennan Kieran</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O TSS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>110 E. OLD SETTLERS BLVD.</rptOwnerStreet2>
            <rptOwnerCity>ROUND ROCK</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>78664</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>Sr. V.P., Sales &amp; Marketing</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <ownerSignature>
        <signatureName>/s/ Kieran Brennan</signatureName>
        <signatureDate>2018-01-24</signatureDate>
    </ownerSignature>
</ownershipDocument>
