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Note 1 - Description of Business (Details Textual)		3 Months Ended
Note 1 - Description of Business (Details Textual)	Jun. 24, 2021 shares	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)	Dec. 31, 2021 USD ($)
Number of Subsidiaries		2
Cash and Cash Equivalents, at Carrying Value, Total		$ 152,183		$ 1,844,732
Retained Earnings (Accumulated Deficit), Total		(137,239,351)		$ (129,482,141)
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total		$ (7,759,933)	$ (5,286,646)
ImQuest [Member]
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares (in shares) \| shares	3,282,089
BioLab 612 [Member]
Number of Wholly Owned Subsidiaries		1
GPI [Member]
Equity Method Investment, Ownership Percentage		50.00%