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Note 10 - Warrants (Tables)
3 Months Ended
Mar. 31, 2022
Notes Tables  
Schedule of Outstanding Warrants [Table Text Block]
  Number of Warrants  Weighted Average Exercise Price 

December 31, 2021

  2,431,168  $4.48 

Granted

  30,777,776   0.46 

Exercised

      

Forfeited, Canceled

      

March 31, 2022

  33,208,944  $0.76