Note 6 - Significant Alliances and Related Parties (Details Textual) - USD ($)	3 Months Ended
Mar. 31, 2020	Mar. 31, 2019
Research and Development Expense, Total	$ 218,208	$ 513,421
RPCI [Member]
Research and Development Expense, Total	1,197	0
The Cleveland Clinic [Member]
Research and Development Expense, Total	0	30,710
BBL [Member]
Research and Development Expense, Total	0	0
Sublease and Other Income, Related Parties	0	11,553
Accounts Receivable, Related Parties, Gross	6,285	222,938
Accounts Receivable, Related Parties	6,285	20,787
Incuron [Member]
Sublease and Other Income, Related Parties	0	1,134
Accounts Receivable, Related Parties, Gross	140,595	134,823
Revenue from Related Parties	41,010	134,067
GPI [Member]
Sublease and Other Income, Related Parties	0	3,031
Related Party Transaction, Expenses from Transactions with Related Party	$ 13,440	$ 47,425

For an unclassified balance sheet, gross amount of receivables arising from transactions with related parties.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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