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Note 3 - Fair Value Measurements (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Fair Value, by Balance Sheet Grouping [Table Text Block]
   
As of December 31, 2019
 
   
Level 1
   
Level 2
   
Level 3
   
Total
 
Assets:
     
 
     
 
     
 
     
 
Cash and cash equivalents
  $
    $
    $
    $
 
Short-term investments
   
     
452,301
     
     
452,301
 
Total assets
  $
    $
452,301
    $
    $
452,301
 
Liabilities:
     
 
     
 
     
 
     
 
Accrued warrant liability
  $
    $
    $
6,414
    $
6,414
 
   
As of December 31, 2018
 
   
Level 1
   
Level 2
   
Level 3
   
Total
 
Assets:
     
 
     
 
     
 
     
 
Cash and cash equivalents
  $
1,130
    $
    $
    $
1,130
 
Short-term investments
   
     
503,810
     
     
503,810
 
Total assets
  $
1,130
    $
503,810
    $
    $
504,940
 
Liabilities:
     
 
     
 
     
 
     
 
Accrued warrant liability
  $
    $
    $
78,637
    $
78,637
 
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
   
Year Ended December 31, 2019
 
Beginning Balance
  $
78,637
 
Total (gains) or losses, realized and unrealized, included in earnings (1)
   
(72,223
)
Balance at December 31, 2019
  $
6,414
 
   
Year Ended December 31, 2018
 
Beginning Balance
  $
1,041,455
 
Total (gains) or losses, realized and unrealized, included in earnings (1)
   
(962,818
)
Balance at December 31, 2018
  $
78,637
 
Fair Value, Assets and Liabilities Measured on Nonrecurring Basis, Valuation Techniques [Table Text Block]
   
December 31, 2019
 
Description
 
Fair Value
 
Valuation Technique
 
Unobservable Input
 
Range in years
 
Accrued warrant liability
  $
6,414
 
Black-scholes pricing model
 
Expected term
   
1.04-1.60
 
Warrant [Member]  
Notes Tables  
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
   
December 31,
 
   
2019
   
2018
 
Stock Price
  $
0.60
    $
1.01
 
Exercise Price
  $
3.64
-
20.40
    $
3.64
-
24.40
 
Term in years
   
1.04-1.60
     
0.04
-
2.60
 
Volatility
   
84.59
-
98.24
%    
88.07
-
108.18
%
Annual rate of quarterly dividends
   
0
%    
0
%
Discount rate- bond equivalent yield
   
1.58
-
1.59
%    
0.12
-
2.48
%