Noncontrolling Interests - Additional Information (Detail)	12 Months Ended		0 Months Ended		0 Months Ended									0 Months Ended			12 Months Ended			12 Months Ended
	Dec. 31, 2013	Dec. 31, 2013 Panacela [Member] USD ($)	Oct. 04, 2011 C B L I [Member] USD ($)	Dec. 31, 2013 C B L I [Member]	May 31, 2012 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] USD ($)	May 31, 2012 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] RUB	Mar. 14, 2011 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] USD ($)	Mar. 14, 2011 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] RUB	Jan. 20, 2011 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] USD ($)	Jan. 20, 2011 Bioprocess Capital Ventures [Member] Incuron, LLC [Member] RUB	Oct. 04, 2011 Rusnano [Member] USD ($)	Dec. 31, 2013 Rusnano [Member] USD ($)	Sep. 03, 2013 Rusnano [Member] USD ($)	Oct. 04, 2011 Rusnano [Member] Panacela [Member] USD ($)	May 31, 2012 Increased To [Member] Bioprocess Capital Ventures [Member]	May 31, 2012 Decreased To [Member] C B L I [Member]	Dec. 31, 2013 Minimum [Member]	Mar. 14, 2011 Minimum [Member] C B L I [Member]	Jan. 20, 2011 Minimum [Member] Bioprocess Capital Ventures [Member]	Dec. 31, 2013 Maximum [Member]	Jan. 20, 2011 Maximum [Member] C B L I [Member]	Mar. 14, 2011 Maximum [Member] Bioprocess Capital Ventures [Member]
Noncontrolling Interest [Line Items]
Payments to Acquire Additional Interest in Subsidiaries					$ 5,900,000	194,000,000	$ 100,000	1,730,000	$ 2,300,000	68,000,000	$ 17,000,000
Noncontrolling interest, ownership percentage by noncontrolling owners				54.60%											40.80%				16.10%			24.20%
Equity method investment, ownership percentage																59.20%		75.80%			83.90%
Payments to Acquire Interest in Subsidiaries and Affiliates (in Dollars)			3,000,000											9,000,000
Debt Instrument, Face Amount													1,500,000
Amount available to be invested at option												$ 15,500,000
Preferred Stock, Redemption Price Per Share (in Dollars per share)		$ 1,057
Exercisable Price Percentage																	20.00%			40.00%
Expiry date of issuance price of preferred stock	2013-10