Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)	12 Months Ended				12 Months Ended									12 Months Ended		0 Months Ended	12 Months Ended
	Dec. 31, 2013 Agreement	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2013 2013 ESPP Plan [Member]	Dec. 31, 2011 Patents [Member]	Dec. 31, 2013 Grant and Contract Revenue from U S A [Member]	Dec. 31, 2012 Grant and Contract Revenue from U S A [Member]	Dec. 31, 2011 Grant and Contract Revenue from U S A [Member]	Dec. 31, 2013 Grant and Contract Revenue from Outside United States [Member]	Dec. 31, 2012 Grant and Contract Revenue from Outside United States [Member]	Dec. 31, 2011 Grant and Contract Revenue from Outside United States [Member]	Dec. 31, 2013 Accounts Receivable [Member]	Dec. 31, 2013 Buffalo BioLabs [Member]	Dec. 31, 2013 Scenario, Previously Reported [Member]	Mar. 11, 2014 Subsequent Event [Member]	Dec. 31, 2013 Cash and Cash Equivalents Located Outside United States [Member]	Dec. 31, 2013 Short Term Investments Located Outside United States [Member]	Dec. 31, 2013 Beyond [Member] Certificates of Deposit [Member]	Dec. 31, 2013 Less Than [Member] Certificates of Deposit [Member]	Dec. 31, 2013 Majority Owned Subsidiaries [Member]	Dec. 31, 2013 General Use [Member]
Accounting Policies [Line Items]
Cash and cash equivalents at carrying value	$ 10,048,466	$ 25,652,083	$ 22,872,589	$ 10,918,537
Other cash and cash equivalents at carrying value	3,500,000	13,000,000
Cash and highly liquid investments maturity	90 days
Subsidiary cash total																					2,000,000
General use cash total																						8,000,000
Short-term investments maturity																			3 months	1 year
Concentration risk percentage							26.80%	34.80%	87.60%	73.20%	65.20%	12.40%					36.00%	100.00%
Russian Ruble exchange rate															32.2792	36.2618
Decrease in company's cash and cash equivalents																350,557
Decrease in company's short-term investment																29,765
Credit term													30 days
Allowances for doubtful accounts	0	0
Date of equipment lease agreement														Jan. 01, 2014
Carrying amount of the equipment	536,000
Fair value of assets	243,000
Write-down of the assets	293,000
Amortization of intangible assets						1,500,000
Number of contractual arrangement	2
Share-based compensation arrangement by share-based payment award, number of shares authorized	10,000,000
Share-based compensation arrangement by share-based payment award, number of shares available for grant	2,100,000				2,100,000
Share-based compensation arrangement by share-based payment award number of shares limited per year	400,000
Share-based compensation arrangement by share-based payment award, equity instruments other than options, outstanding, weighted average remaining contractual terms	10 years
Percentage of the total number of shares of common stock outstanding of the preceding year					10.00%
Share-based compensation arrangement by share-based payment award, number of shares limited per year					200,000
Share-based compensation arrangement by share-based payment award, maximum employee subscription rate					15.00%
Share-based compensation arrangement by share-based payment award, discount from market price, offering rate					85.00%
Income tax expense