Stockholders' Equity (Tables)

12 Months Ended

Dec. 31, 2013

Schedule of Stockholders' Equity Note, Warrants or Rights

The following table sets forth the changes in the number of warrants outstanding for the periods presented, exclusive of the warrants issued to Rusnano in connection with their loan to Panacela as those warrants are not exercisable until an event of default which has not occurred:


	Number of Warrants			Weighted Average Exercise Price		Number of Common Shares Exercisable Into
Outstanding at December 31, 2011		10,121,219		$	3.76		12,564,193
Granted		4,312,500			3.00		4,312,500
Forfeited, Canceled		(4,055,724	)		5.07		(6,498,698	)

Outstanding at December 31, 2012		10,377,995			2.94		10,377,995
Granted		156,250			1.60		156,250

Outstanding at December 31, 2013		10,534,245			2.70		10,534,245

Schedule of Share-Based Compensation Shares Authorized Under Warrants by Exercise Price Range

The following table sets forth the details of the outstanding warrants as of December 31, 2013:


Expiration Date	Current Exercise Price		Number of Warrants
March 2, 2015	$	1.60		935,385
June 17, 2015		5.00		176,175
February 12, 2016		1.60		929,826
March 19, 2016		1.60		1,921,795
March 26, 2016		1.60		634,189
June 22, 2016		5.00		1,468,125
October 24, 2017		3.00		4,312,500
September 30, 2018		1.60		156,250

				10,534,245

Schedule of Share-based Compensation, Stock Options Activity

The following is a summary of option award activity under the Plan for the year ended December 31, 2013:


	Year Ended December 31, 2013
	Total Stock Options Outstanding			Weighted Average Exercise Price per Share		Nonvested Stock Options			Weighted Average Grant Date Fair Value per Share
December 31, 2012		5,016,916		$	4.54		404,500		$	2.30
Granted		903,775			1.67		903,775			1.21
Vested		—			—		(513,296	)		1.73
Exercised		(9,681	)		1.28		—			—
Forfeited, Canceled		(346,177	)		3.53		(200,500	)		1.21

December 31, 2013		5,564,833			4.14		594,479			1.50

Schedule of Share-based Compensation, Activity

The following is a summary of outstanding stock options under the Plan as of December 31, 2013:


	Stock Options Outstanding		Vested Stock Options
Quantity		5,564,833		4,970,354
Weighted-average exercise price	$	4.14	$	4.40
Weighted Average Remaining Contractual Term (in Years)		6.75		6.47
Intrinsic value	$	11,592	$	11,592

- Definition

Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable.

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