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Consolidated Statements of Cash Flows (Unaudited) (USD $)
9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Cash flows from operating activities:    
Net loss $ (19,284,530) $ (24,621,440)
Adjustments to reconcile net income (loss) to net cash used in operating activities:    
Depreciation 284,278 376,814
Unrealized loss on short-term investments   138,910
Noncash compensation 1,591,986 2,272,020
Change in value of warrant liability (510,919) 160,749
Changes in operating assets and liabilities:    
Accounts receivable (565,336) 1,695,870
Other current assets 452,798 (435,305)
Other long-term assets (3,995) (2,554)
Accounts payable (310,150) (471,635)
Deferred revenue (1,102,472) 3,821,991
Accrued interest 18,448  
Accrued expenses 506,750 1,609,369
Net cash used in operating activities (18,923,142) (15,455,211)
Cash flows from investing activities:    
Purchase of short-term investments   (4,898,314)
Sale of short-term investments 2,213,999 3,560,812
Purchase of equipment (125,218) (154,742)
Increase in restricted cash (1,421,861)  
Net cash provided by (used in) investing activities 666,920 (1,492,244)
Cash flows from financing activities:    
Noncontrolling interest capital contribution to Incuron, LLC   5,893,557
Net proceeds from issuance of debt 7,297,675  
Exercise of options 12,392 1,425
Repayment of capital lease obligation (59,012) (36,029)
Net cash provided by financing activities 7,251,055 5,858,953
Effect of exchange rate change on cash and equivalents (333,995) 404,486
Decrease in cash and cash equivalents (11,339,162) (10,684,016)
Cash and cash equivalents at beginning of period 25,652,083 22,872,589
Cash and cash equivalents at end of period 14,312,921 12,188,573
Supplemental disclosure of cash flow information:    
Cash paid during the period for interest 17,105 17,253
Supplemental schedule of noncash financing activities:    
Fair value of warrants issued in connection with debt 117,999  
Equipment acquired through lease financing   $ 221,690