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Note 2 - Summary of significant accounting policies (Tables)

3 Months Ended

Mar. 31, 2013

Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Method Used

	For the three months ended March 31,
	2013			2012

Risk-free interest rate	.93	-	1.00%	.91	-	1.49%
Expected dividend yield	0%			0%
Expected life (years)	5	-	6	5	-	6
Expected volatility	88.54	-	89.60%	86.58	-	90.05%

Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]

	As of March 31,
Common Equivalent Securities	2013		2012

Warrants		10,377,995		7,533,620
Options		4,966,753		4,353,512

Total		15,344,748		11,887,132

- Definition

For each plan, identification of the award pricing model or other valuation method used in calculating the weighted average fair values disclosed. The model is also used to calculate the compensation expense that is shown within the balance sheet, income statement, and cash flow. Examples of valuation techniques are lattice models (binomial model), closed-form models (Black-Scholes-Merton formula), and a Monte Carlo simulation technique. Fair value is the amount at which an asset or liability could be bought or incurred or sold or settled in a current transaction between willing parties, that is, other than in a forced or liquidation sale. May include disclosures about the assumptions underlying application of the method selected.

+ References+ Details