Consolidated Statement of Stockholders' Equity (Deficit) (USD $)	Common Stock [Member]	Preferred Stock [Member]	Additional Paid-in Capital [Member] Incuron [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Retained Earnings [Member]	Noncontrolling Interest [Member] Incuron [Member]	Noncontrolling Interest [Member] Panacela [Member]	Noncontrolling Interest [Member]	Incuron [Member]	Panacela [Member]	Total
Balance at January 1, 2010 at Dec. 31, 2009	$ 101,018	$ 2		$ 62,786,418		$ (69,687,932)						$ (6,800,494)
Balance at January 1, 2010 (in Shares) at Dec. 31, 2009	20,203,508	467
Issuance of	14,692			12,133,212								12,147,904
Issuance of (in Shares)	2,938,462
Allocation of financing proceeds to fair value of warrants				(2,629,847)								(2,629,847)
Conversion of preferred shares to common shares	22,885	(2)		(22,883)
Conversion of preferred shares to common shares (in Shares)	4,576,979	(467)
Noncontrolling interest capital contribution to subsidiary									3,509,564			3,509,564
Exercise of options	1,683			900,228								901,911
Exercise of options (in Shares)	336,674
Exercise of warrants	2,212			2,436,745								2,438,957
Exercise of warrants (in Shares)	442,357
Stock based compensation	2,306			4,637,844								4,640,150
Stock based compensation (in Shares)	461,196
Net loss						(26,366,045)			(305,812)			(26,671,857)
Foreign currency translation					(30,544)				(5,879)			(36,423)
Balance at Dec. 31, 2010	144,796			80,241,717	(30,544)	(96,053,977)			3,197,873			(12,500,135)
Balance (in Shares) at Dec. 31, 2010	28,959,176
Issuance of	29,363			21,840,999								21,870,362
Issuance of (in Shares)	5,872,500
Allocation of financing proceeds to fair value of warrants				(2,525,175)								(2,525,175)
Noncontrolling interest capital contribution to subsidiary			176,092				2,164,282	9,000,066		2,340,374	9,000,066
Exercise of options	951			531,457								532,408
Exercise of options (in Shares)	190,255
Exercise of warrants	1,407			1,943,813								1,945,220
Exercise of warrants (in Shares)	281,411
Stock based compensation	1,544			6,656,742								6,658,286
Stock based compensation (in Shares)	308,850
Net loss						(4,013,670)			(1,216,055)			(5,229,725)
Foreign currency translation					115,157				38,658			153,815
Balance at Dec. 31, 2011	178,061			108,865,645	84,613	(100,067,647)			13,184,824			22,245,496
Balance (in Shares) at Dec. 31, 2011	35,612,192
Issuance of	42,625			15,877,959								15,920,584
Issuance of (in Shares)	8,525,000
Allocation of financing proceeds to fair value of warrants				(4,521,681)								(4,521,681)
Noncontrolling interest capital contribution to subsidiary			1,081,040				4,812,517			5,893,557
Exercise of options	6			2,369								2,375
Exercise of options (in Shares)	1,250											(1,250)
Stock based compensation	2,961			2,559,498								2,562,459
Stock based compensation (in Shares)	592,003
Net loss						(18,234,142)			(4,180,498)			(22,414,640)
Foreign currency translation					461,860				335,698			797,558
Balance at Dec. 31, 2012	$ 223,653			$ 123,864,830	$ 546,473	$ (118,301,789)			$ 14,152,541			$ 20,485,708
Balance (in Shares) at Dec. 31, 2012	44,730,445