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Consolidated Statements of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Cash flows from operating activities:      
Net loss $ (5,229,725) $ (26,671,857) $ (12,826,409)
Depreciation 512,366 389,439 357,568
Amortization 13,147 17,850 4,575
Noncash compensation 4,044,858 6,662,130 3,730,646
Warrant issuance costs 150,827 231,980 266,970
Change in value of warrant liability (19,821,787) 16,011,769 6,267,665
Patent costs 1,481,318   35,564
Changes in operating assets and liabilities:      
Accounts receivable 3,641,491 (1,990,774) (2,347,526)
Other current assets 123,197 (611,885) 139,165
Other long-term assets (919) (8,656)  
Accounts payable (348,282) 53,370 106,672
Deferred revenue (2,317,218) (12,398) (35,696)
Accrued expenses 1,088,556 (35,109) (208,279)
Accrued bonuses (243,219) 64,810 264,141
Net cash used in operating activities (16,905,390) (5,899,331) (4,244,944)
Cash flows from investing activities:      
Purchase of short-term investments (5,520,000) (459,364)  
Sale of short-term investments 434,835   1,000,000
Purchase of equipment (655,553) (465,650) (136,400)
Investment in patents (326,171) (250,735) (237,064)
Net cash provided by (used in) investing activities (6,066,889) (1,175,749) 626,536
Cash flows from financing activities:      
Net proceeds from issuance of preferred stock     4,441,162
Net proceeds from issuance of common stock 21,946,801 12,234,693  
Preferred stock dividends     (936,644)
Exercise of options 532,408 901,911 362,857
Exercise of warrants 949,793 418,926 414,284
Net cash provided by financing activities 34,769,442 17,065,094 4,281,659
Effect of exchange rate change on cash and equivalents 156,889 (34,577)  
Increase in cash and cash equivalents 11,954,052 9,955,437 663,251
Cash and cash equivalents at beginning of year 10,918,537 963,100 299,849
Cash and cash equivalents at end of year 22,872,589 10,918,537 963,100
Supplemental schedule of noncash financing activities:      
Conversion of warrant liability to equity upon warrant exercise 995,428 2,020,031 874,120
Financing Costs [Member]
     
Supplemental schedule of noncash financing activities:      
Noncash financing costs on common stock offering 207,905 227,486  
Noncash warrant issuance costs 207,905 227,486  
Warrant Issue Costs [Member]
     
Supplemental schedule of noncash financing activities:      
Noncash financing costs on common stock offering 19,361 91,283  
Noncash warrant issuance costs 19,361 91,283  
Incuron LLC [Member]
     
Cash flows from financing activities:      
Noncontrolling interest capital contribution to Incuron, LLC 2,340,374 3,509,564  
Noncontrolling interest capital contribution to Panacela Labs, Inc. 2,340,374 3,509,564  
Panacela Labs Inc [Member]
     
Cash flows from financing activities:      
Noncontrolling interest capital contribution to Incuron, LLC 9,000,066    
Noncontrolling interest capital contribution to Panacela Labs, Inc. $ 9,000,066