CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation in this Registration Statement on Form SB-2 of Cleveland BioLabs, Inc. of our report dated February 7, 2006 relating to the financial statements. We also consent to the reference to us as “Experts” under the heading “Experts” in such Registration Statement.

/s/ Meaden & Moore, Ltd.

MEADEN & MOORE, LTD.

Independent Registered Public Accounting Firm

February 17, 2006

Cleveland, Ohio