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Note 11 - Right-of-use Assets - Right-of-use Assets (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Operating lease right-of-use assets $ 134,914
Initial recognition of operating lease right-of-use assets   76,557
Capitalization of operating lease right-of-use assets   125,474
Amortization of operating lease right-of use assets (15,372) $ (12,560) (72,416)
Operating lease right-of-use assets 128,210   134,914
Facility in Vancouver, Canada [Member]      
Capitalization of operating lease right-of-use assets   125,474
Operating Lease, License Agreement [Member]      
Capitalization of operating lease right-of-use assets $ 8,668   $ 5,299