X0202 4 2007-11-06 0 0001318310 ev3 Inc. evvv 0001007708 SIMPSON JOHN B PH D MD C/O EV3 INC. 9600 54TH AVENUE NORTH, SUITE 100 PLYMOUTH MN 55442 1 1 0 0 Vice Chairman/Chief Scientist Common Stock 2007-11-06 5 G 0 E 254676 0 D 0 I By John Bush Simpson Annuity Trust Common Stock 2007-11-06 5 G 0 E 254676 0 D 0 I By Rita Lynn Simpson Annuity Trust Common Stock 6635858 I By Simpson Family Trust Common Stock 800263 I By JD Simpson Trust No. 2 Common Stock 292787 I By FoxHollow, L.P. Common Stock 325989 I By John Bush Simpson Annuity Trust 3 Common Stock 325989 I By Rita Lynn Simpson Annuity Trust 3 Common Stock 53832 I By spouse Common Stock 16988 D Reflects the distribution of 73,365 shares of common stock from each of the Rita Lynn Simpson Annuity Trust and the John Bush Simpson Annuity Trust to the Simpson Family Trust and the distribution of an aggregate of 254,676 shares of common stock from each of the Rita Lynn Simpson Annuity Trust and the John Bush Simpson Annuity Trust to the beneficiaries of the annuity trusts for no consideration. These shares are held by the Simpson Family Trust, of which Dr. Simpson serves as a trustee. Dr. Simpson disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. These shares are held by the JD Simpson Trust No. 2, of which Dr. Simpson serves as a trustee. The shares are held in a trust for the benefit of Dr. Simpson's son, of which Dr. Simpson serves as a trustee. Dr. Simpson disclaims beneficial ownership of these shares, and the filing of this report is not an admission that Dr. Simpson is a beneficial owner of these shares for purposes of Section 16 or for any other purpose. These shares are held by FoxHollow, L.P., a California Limited Partnership, of which Dr. Simpson serves as a managing member. Dr. Simpson disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. Includes 16,447 shares of common stock issued pursuant to a restricted stock grant under the ev3 Inc. Second Amended and Restated 2005 Stock Incentive Plan and still subject to forfeiture. /s/ John B. Simpson, Ph.D. 2007-11-27