<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-04-06</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001317833</issuerCik>
        <issuerName>SIGNET INTERNATIONAL HOLDINGS, INC.</issuerName>
        <issuerTradingSymbol>SIGN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001923128</rptOwnerCik>
            <rptOwnerName>Yeung Carter</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GOLDEN ALLY LIFETECH GROUP, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>901 S MOPAC EX., BLDG. 1, SUITE 300</rptOwnerStreet2>
            <rptOwnerCity>AUSTIN</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>78746</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Marketing Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000000</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The reporting person is a non-controlling member of Commonwealth Investments LLC, which owns 2,500,000,000 shares of Common Stock of the Issuer.  The reporting person does not have or share investment control over such shares, and therefore, he disclaims any pecuniary interest in such shares.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Oliver Keren Ban, as attorney in fact for the Reporting Person</signatureName>
        <signatureDate>2022-04-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
