8-K

United States

Securities and Exchange Commission

Washington, DC 20549

Form 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported)  April 23, 2008

AMERICAN CARESOURCE HOLDINGS, INC.

(Exact Name of Registrant as Specified in its Charter)

Delaware	001-33094	20-0428568
(State or Other Jurisdiction of Incorporation)	(Commission File Number)	(IRS Employer Identification No.)

5429 Lyndon B. Johnson Freeway, Suite 700, Dallas, Texas	75240
(Address of Principal Executive Offices)	(Zip Code)

Registrant’s telephone number, including area code (972) 308-6830

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2.)

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

ITEM 2.02 Results of Operations and Financial Condition

On April 23, 2008, American CareSource Holdings, Inc. (the “Registrant”) issued a press release announcing its revenues for the first quarter ended March 31, 2008.  A copy of the press release is attached hereto as Exhibit 99.1.

In accordance with General Instruction B-2 of Current Report on Form 8-K, the information in this Current Report on Form 8-K is furnished under Item 2.02 - “Results of Operations and Financial Condition.”  The information presented herein, included the exhibit attached hereto, shall not be deemed to be “filed” for any purpose, including for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section.  The information in this Current Report on Form 8-K shall not be deemed incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act except as expressly set forth by specific reference in such a filing.

ITEM 9.01 Financial Statements and Exhibits

(a)           Financial Statements of Businesses Acquired:

None.

(b)           Pro Forma Financial Information:

None.

(c)           Shell Company Transactions:

None.

(d)           Exhibits

This exhibit is furnished pursuant to Item 2.02 and shall not be deemed to be “filed.”

99.1 Press release of Registrant dated April 23, 2008

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	AMERICAN CARESOURCE HOLDINGS, INC.
Date: April 23, 2008	By:	/s/ Steven J. Armond
		Steven J. Armond
		Chief Financial Officer

Exhibit Index

Exhibit No.	Description
99.1	Press release of Registrant dated April 23, 2008

EX-99.1

Contact:

David S. Boone

Chief Executive Officer

American CareSource Holdings, Inc.

Tel: 972-308-6830

FOR IMMEDIATE RELEASE

AMERICAN CARESOURCE HOLDINGS REPORTS 407% INCREASE IN REVENUES FOR FIRST QUARTER 2008

DALLAS, TX – April 23, 2008 -- American CareSource Holdings, Inc. (AMEX: XSI) today reported a 407% increase in revenues to approximately $11.5 million for the first quarter ended March 31, 2008 compared to approximately $2.3 million in the same period last year.  The Company’s first quarter revenues also represent a 14% improvement over fourth quarter 2007 reported revenues of $10.1 million.

“Our first quarter 2008 revenues continued the strong upward trend we began last year and are a direct reflection of the ongoing strength in demand for our expanding array of outsourced ancillary services, among both new and existing clients,” noted David S. Boone, Chief Executive Officer of American CareSource.  “We are on track to exceed our initial guidance of $50 million for full year 2008 revenues. We are looking forward to future announcements of new customer wins, expansion of our provider network and continued strong organic growth in the coming months.”

American CareSource will host a conference call to discuss the first quarter financial results on Thursday, May 15, 2008 at 10:00 a.m. central time.  The Company will issue a press release reporting full financial results the same morning.

About American CareSource Holdings, Inc.

American CareSource Holdings, the first national, publicly traded ancillary care network services company, offers a comprehensive national network of approximately 25,000 ancillary provider sites. Through its product offerings, American CareSource helps its clients reduce the cost of ancillary services rendered through its network of providers in more than 30 service categories. The Company's ancillary network and management provides a complete outsourced solution for a wide variety of healthcare payors and plan sponsors including self-insured employers, indemnity insurers, PPOs, HMOs, third party administrators and both federal and local governments.

Any statements in this release that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995.  It is possible that the assumptions made by American CareSource Holdings, Inc. for purposes of such statements may not materialize.  Actual results may differ materially from those projected or implied in any forward-looking statements.  Such statements may involve further risks and uncertainties, including, but not limited to, our inability to continue partnering with our clients, our inability to continue to experience growth and the risk that, even with increases in revenue, we may not be able to experience earnings on a sustained level, the risks associated with product development and of market demand for our products, competitive forces, our inability to adequately protect our intellectual property rights, downturns in national and local economies and economic conditions in the healthcare industry, the effect of changes in governmental regulations in the healthcare industry, and other risks identified from time to time in the Securities and Exchange Commission filings of American CareSource Holdings, Inc.

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