X0303 4/A 2010-12-31 2011-01-04 0 0001316175 Anthera Pharmaceuticals Inc ANTH 0001376260 LOWE CHRISTOPHER P. C/O ANTHERA PHARMACEUTICALS, INC. 25801 INDUSTRIAL BOULEVARD, SUITE B HAYWARD CA 94545 0 1 0 0 CFO & VP of Administration Common Stock 67645 D Common Stock 9637 I By spouse Common Stock 80997 I By BioVest III Stock Option (right to buy) 4.88 2010-12-31 4 A 0 160000 0.00 A 2020-12-31 Common Stock 160000 160000 D Includes 5,122 shares acquired under the Issuer's 2010 Employee Stock Purchase Plan on December 31, 2010. The number of shares acquired by the Reporting Person under the Issuer's 2010 Employee Stock Purchase Plan on December 31, 2010 contained a typographical error and, therefore, was incorrectly reported in the Reporting Person's original Form 4. Mr. Lowe is a principal of BioVest III, which directly holds the reported securities, and as such, may be deemed to have sole voting and investment power with respect to such securities. The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose. The Stock Option vests and becomes exercisable in accordance with the following vesting schedule: 25% of the total number of shares vest on the first anniversary of the December 15, 2010 vesting start date (the "Vesting Start Date") and pro-rata monthly thereafter. This Stock Option is completely vested on the fourth anniversary of the Vesting Start Date. /s/ Mitzi Chang, by power of attorney 2011-01-07