0001144204-18-064515.txt : 20181213 0001144204-18-064515.hdr.sgml : 20181213 20181213183025 ACCESSION NUMBER: 0001144204-18-064515 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20181211 FILED AS OF DATE: 20181213 DATE AS OF CHANGE: 20181213 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: RA CAPITAL MANAGEMENT, LLC CENTRAL INDEX KEY: 0001346824 STATE OF INCORPORATION: MA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-38756 FILM NUMBER: 181234203 BUSINESS ADDRESS: STREET 1: 20 PARK PLAZA, SUITE 1200 CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 617-778-2500 MAIL ADDRESS: STREET 1: 20 PARK PLAZA, SUITE 1200 CITY: BOSTON STATE: MA ZIP: 02116 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: RA Capital Healthcare Fund LP CENTRAL INDEX KEY: 0001315082 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-38756 FILM NUMBER: 181234204 BUSINESS ADDRESS: STREET 1: 20 PARK PLAZA, SUITE 1200 CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 6177782500 MAIL ADDRESS: STREET 1: 20 PARK PLAZA, SUITE 1200 CITY: BOSTON STATE: MA ZIP: 02116 FORMER NAME: FORMER CONFORMED NAME: RA Capital Biotech Fund LP DATE OF NAME CHANGE: 20050121 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Synthorx, Inc. CENTRAL INDEX KEY: 0001609727 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 464709185 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 11099 NORTH TORREY PINES ROAD, SUITE 290 CITY: LA JOLLA STATE: CA ZIP: 92037 BUSINESS PHONE: 858-750-4715 MAIL ADDRESS: STREET 1: 11099 NORTH TORREY PINES ROAD, SUITE 290 CITY: LA JOLLA STATE: CA ZIP: 92037 4 1 tv509134_4.xml OWNERSHIP DOCUMENT X0306 4 2018-12-11 0 0001609727 Synthorx, Inc. THOR 0001346824 RA CAPITAL MANAGEMENT, LLC C/O RA CAPITAL MANAGEMENT, LLC 20 PARK PLAZA, SUITE 1200 BOSTON MA 02116 0 0 1 0 0001315082 RA Capital Healthcare Fund LP C/O RA CAPITAL MANAGEMENT, LLC 20 PARK PLAZA, SUITE 1200 BOSTON MA 02116 0 0 1 0 Common Stock 2018-12-11 4 C 0 1525235 A 1525235 I See Footnote Common Stock 2018-12-11 4 C 0 3653908 A 5179143 I See Footnote Common Stock 2018-12-11 4 P 0 4545455 11.00 A 9724598 I See Footnote Series B Preferred Stock 2018-12-11 4 C 0 2443794 0 D Common Stock 1525235 0 I See Footnote Series C Preferred Stock 2018-12-11 4 C 0 5854439 0 D Common Stock 3653908 0 I See Footnote Automatic conversion, in connection with the Issuer's initial public offering, of preferred stock into shares of common stock on a 1.60224-to-1 basis. The shares are held as follows: 1,245,659 shares held by RA Capital Healthcare Fund, L.P. (the "Fund") and 279,576 shares held by a separately managed account (the "Account"). RA Capital Management, LLC (the "Adviser") is the general partner of the Fund and the investment adviser for the Account and therefore may be deemed to beneficially own the reported securities for purposes of Section 13(d) of the Securities Exchange Act of 1934. Additionally, Peter Kolchinsky is a director of the Issuer and the sole manager of the Adviser. The Adviser disclaims beneficial ownership of the reported securities for purposes of Rule 16a-1(a)(1) under the Exchange Act in reliance on Rule 16a-1(a)(1)(v) and therefore disclaims any obligation to report ownership of the reported securities under Section 16(a) of the Exchange Act. The filing of this Form 4 shall not be construed as an admission that the Adviser is, for purposes of Rule 16a-1(a)(1) under the Exchange Act, the beneficial owner of any of the securities reported herein. The Adviser disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a)(2) under the Exchange Act except to the extent of its pecuniary interest therein. The shares are held as follows: 2,941,397 shares held by the Fund and 712,511 shares held by the Account. The shares were purchased at the Issuer's initial public offering. These securities include 7,968,645 shares held by the Fund and 1,755,953 shares held by the Account. /s/ Peter Kolchinsky, Manager of RA Capital Management, LLC 2018-12-13 /s/ Peter Kolchinsky, Manager of RA Capital Management, LLC the General Partner of RA Capital Healthcare Fund, L.P. 2018-12-13