BlackRock Health Sciences Trust

Cusip: 09250W107

Ticker: BME

Record Date		December 16, 2022
Pay Date		December 30, 2022
Distribution Amount per share	$	0.213000

The following table sets forth the estimated amounts of the current distribution and the cumulative distributions paid this fiscal year to date from the following sources: net income, net realized short-term capital gains, net realized long-term capital gains and return of capital. All amounts are expressed per common share.

							% Breakdown of the
			% Breakdown of		Total Cumulative		Total Cumulative
			the Current		Distributions for the		Distributions for the
	Current Distribution		Distribution		Fiscal Year to Date		Fiscal Year to Date
Net Income	$	0.032998		15%	$	0.106430		4%
Net Realized Short-Term Capital Gains	$	-		0%	$	-		0%
Net Realized Long-Term Capital Gains	$	-		0%	$	2.266920		89%
Return of Capital	$	0.180002		85%	$	0.182650		7%
Total (per common share)	$	0.213000		100%	$	2.556000		100%
Average annual total return (in relation to NAV) for the 5-year period ending on November 30, 2022								10.44%
Annualized current distribution rate expressed as a percentage of NAV as of November 30, 2022								5.80%
Cumulative total return (in relation to NAV) for the fiscal year through November 30, 2022								-3.02%
Cumulative fiscal year distributions as a percentage of NAV as of November 30, 2022								5.32%

You should not draw any conclusions about the Trust’s investment performance from the amount of this distribution or from the terms of the Trust’s Managed Distribution Plan.

The Fund estimates that it has distributed more than its income and net realized capital gains; therefore, a portion of your distribution may be a return of capital. A return of capital may occur, for example, when some or all of the money that you invested in the Fund is paid back to you. A return of capital does not necessarily reflect the Fund’s investment performance and should not be confused with ‘yield’ or ‘income’.

When distributions exceed total return performance, the difference will reduce the Fund’s net asset value per share.

The amounts and sources of distributions reported in this Notice are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund’s investment experience during its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Contact Number: 800-882-0052

BlackRock Health Sciences Trust

Cusip: 09250W107

Ticker: BME

Record Date		January 13, 2023
Pay Date		January 31, 2023
Distribution Amount per share	$	0.213000

The following table sets forth the estimated amounts of the current distribution and the cumulative distributions paid this fiscal year to date from the following sources: net income, net realized short-term capital gains, net realized long-term capital gains and return of capital. All amounts are expressed per common share.

							% Breakdown of the
			% Breakdown of		Total Cumulative		Total Cumulative
			the Current		Distributions for the		Distributions for the
	Current Distribution		Distribution		Fiscal Year to Date		Fiscal Year to Date
Net Income	$	0.003668		1%	$	0.003668		1%
Net Realized Short-Term Capital Gains	$	0.150197		71%	$	0.150197		71%
Net Realized Long-Term Capital Gains	$	0.059135		28%	$	0.059135		28%
Return of Capital	$	-		0%	$	-		0%
Total (per common share)	$	0.213000		100%	$	0.213000		100%
Average annual total return (in relation to NAV) for the 5-year period ending on December 31, 2022								10.31%
Annualized current distribution rate expressed as a percentage of NAV as of December 31, 2022								5.90%
Cumulative total return (in relation to NAV) for the fiscal year through December 31, 2022								-4.19%
Cumulative fiscal year distributions as a percentage of NAV as of December 31, 2022								5.90%

You should not draw any conclusions about the Trust’s investment performance from the amount of this distribution or from the terms of the Trust’s Managed Distribution Plan.

The amounts and sources of distributions reported in this Notice are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund’s investment experience during its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Contact Number: 800-882-0052