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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Cash flows from operating activities:    
Net loss $ (45,394) $ (56,793)
Adjustments to reconcile net loss to cash flows used in operating activities:    
Amortization of intangible assets 2,460 2,460
Depreciation of property and equipment 189 144
Amortization of debt discount 745 596
Non-cash interest expense 977 1,052
Loss on extinguishment of debt 905 3,810
Stock-based compensation 5,547 4,568
Changes in operating assets and liabilities:    
Accounts receivable and other current assets 4,846 (15,304)
Inventory (3,200) (1,859)
Accounts payable and accrued expenses 1,872 4,596
Right-of-use assets and operating lease liabilities 72 46
Deferred revenue 16,546 (15)
Net cash used in operating activities (14,435) (56,699)
Cash flows from investing activities:    
Purchases of property and equipment (362) (213)
Net cash used in investing activities (362) (213)
Cash flows from financing activities:    
Proceeds from issuance of stock, net of issuance costs 49,918 22,627
Proceeds under paycheck protection program loan 2,041  
Proceeds from issuance of long-term debt   50,000
Payment of debt issue costs   (1,341)
Payment of long-term debt principal (13,794) (20,000)
Payment of extinguishment of debt costs (828) (2,716)
Net settlement of stock units to satisfy statutory tax withholding (90) (120)
Proceeds from exercise of stock options 294 414
Payment of contingent development milestone   (15,000)
Principal payments on finance lease obligations (49)  
Net cash provided by financing activities 37,492 33,864
Effect of foreign exchange rate changes on cash and cash equivalents   1
Net increase (decrease) in cash, cash equivalents and restricted cash 22,695 (23,047)
Cash, cash equivalents and restricted cash at beginning of year 22,364 45,411
Cash, cash equivalents and restricted cash at end of year 45,059 22,364
Supplemental cash flow information:    
Cash interest paid 5,510 4,870
Supplemental disclosure of non-cash investing and financing activities:    
Accrued term loan exit fee $ 122 $ 3,000