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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash flows from operating activities:    
Net loss $ (26,124,000) $ (30,736,000)
Adjustments to reconcile net loss to cash flows used in operating activities:    
Amortization of intangible assets 1,230,000 1,230,000
Depreciation of property and equipment 88,000 78,000
Amortization of debt discount 348,000 270,000
Non-cash interest expense 647,000 406,000
Loss on extinguishment of debt 0 3,810,000
Stock-based compensation 1,895,000 2,734,000
Changes in operating assets and liabilities:    
Accounts receivable and other current assets 4,472,000 (10,681,000)
Inventory (1,635,000) (1,392,000)
Accounts payable and accrued expenses (2,342,000) 3,826,000
Right-of-use assets and operating lease liabilities (30,000) 44,000
Deferred revenue (15,000) (30,000)
Net cash used in operating activities (21,466,000) (30,441,000)
Cash flows from investing activities:    
Purchases of property and equipment (42,000) (207,000)
Net cash used in investing activities (42,000) (207,000)
Cash flows from financing activities:    
Proceeds from issuance of stock, net of issuance costs 19,990,000 18,343,000
Proceeds from issuance of long-term debt   50,000,000
Payment of contingent development milestone   (15,000,000)
Payment of debt issue costs   (1,341,000)
Payment of long-term debt principal   (20,000,000)
Payment of extinguishment of debt costs   (2,716,000)
Net settlement of stock units to satisfy statutory tax withholding (90,000) (46,000)
Proceeds from exercise of stock options and employee stock purchase plan 187,000 308,000
Principal payments on finance lease obligations (20,000)  
Net cash provided by financing activities 22,108,000 29,548,000
Effect of foreign exchange rate changes on cash and cash equivalents 0 0
Net increase (decrease) in cash, cash equivalents and restricted cash 600,000 (1,100,000)
Cash, cash equivalents and restricted cash at beginning of period 22,364,000 45,411,000
Cash, cash equivalents and restricted cash at end of period 22,964,000 44,311,000
Supplemental cash flow information:    
Cash interest paid 1,299,000 1,175,000
Supplemental disclosure of non-cash investing and financing activities:    
Accrued term loan exit fee   $ 3,000,000
Paycheck Protection Program Loan [Member] | Silicon Valley Bank [Member] | CARES Act [Member]    
Cash flows from financing activities:    
Proceeds from issuance of long-term debt $ 2,041,000