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Stockholders' Equity - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended
Jan. 31, 2016
Dec. 31, 2013
Sep. 30, 2016
Sep. 30, 2015
Class of Stock [Line Items]        
Number of warrants     623,605 1,176,105
Weighted Average Exercise Price     $ 2.50 $ 3.67
Number of Warrants, Expired 552,500      
Exercise price of expired warrants $ 5.00      
Remaining contractual life of warrants     10 months  
Weighted-average grant date fair value, per share     $ 2.29  
Options vested during the period     875,003  
Unrecognized compensation expense     $ 2,800,000  
Unrecognized compensation expense weighted average period     2 years 2 months 12 days  
At-the-Market Offering [Member]        
Class of Stock [Line Items]        
Common stock shares maximum aggregate offering price   $ 19,200,000    
Common stock unsold value     $ 17,600,000  
Stock issuances, sales agent commission maximum percentage   3.00% 3.00%  
Common stock issued     0 0
Agreement transaction costs   $ 153,000    
2008 Incentive Plan [Member]        
Class of Stock [Line Items]        
Number of common stock, authorized for issuance     7,841,255  
Shares available for grant     966,741  
Options granted with annual vesting     1,105,300  
Contractual life of option grants     10 years  
2008 Incentive Plan [Member] | Employees [Member]        
Class of Stock [Line Items]        
Options granted with annual vesting     1,105,300  
Ratable annual vesting period of granted options     4 years  
General and Administrative Expense [Member]        
Class of Stock [Line Items]        
Increase in stock-based compensation expense attributable to option modification to extend exercise period of vested stock options, net of non-vested option forfeitures     $ 274,000  
Research and Development Expense [Member] | U.K. [Member]        
Class of Stock [Line Items]        
Decrease in stock-based compensation expense attributable to stock option forfeitures, net of option modification to extend exercise period of vested stock options     $ (35,000)