Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands			12 Months Ended
	Jan. 05, 2024	Dec. 18, 2023	Dec. 31, 2024	Dec. 31, 2023
Related Party Transaction [Line Items]
Research and development expense			$ 132,926	$ 64,662
Revenues			43,273	46,018
Total stock-based compensation expense			36,740	12,057
Prepaid expenses			2,339	1,695
License and Collaboration Agreement [Member]
Related Party Transaction [Line Items]
Revenues			38,496	30,797
Eyebiotech License Agreement [Member] | License and Collaboration Agreement [Member]
Related Party Transaction [Line Items]
Revenues			500
Altasciences Company Inc [Member]
Related Party Transaction [Line Items]
Research and development expense			1,500	1,900
Accounts payable			$ 400	$ 300
Other Liability, Related Party [Extensible Enumeration]			Accounts Payable, Current	Accounts Payable, Current
Prepaid expenses			$ 200	$ 500
Dr. John Landis [Member]
Related Party Transaction [Line Items]
Total stock-based compensation expense			$ 400
Annual Compensation Payment		$ 600
Dr. John Landis [Member] | Restricted Stock Units (RSUs) [Member]
Related Party Transaction [Line Items]
Number of Stock Units, Granted	10,000
Dr. John Landis [Member] | Employee Stock Option
Related Party Transaction [Line Items]
Number of Options, Granted	20,000
Contractual life of option grants	1 year
Dr. John Landis [Member] | Board Stock Option Award [Member]
Related Party Transaction [Line Items]
Number of Options, Granted	25,014