Income Taxes - Reconciliation of U.S. Federal Statutory Income Tax Rate to Effective Income Tax Rate (Detail)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Income Tax Disclosure [Abstract]
Federal statutory income tax rate	21.00%	21.00%
State income taxes, net of federal benefit	7.10%	7.50%
Research and development tax credits	1.20%	1.30%
Permanent items	0.90%	(0.50%)
Changes in valuation allowance	(29.80%)	(30.40%)
Other, net	(0.50%)	1.00%
Effective income tax rate	(0.10%)	(0.10%)