CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Revenues:
Total revenues	$ 9,105	$ 11,565	$ 16,788	$ 20,859
Operating expenses:
Cost of sales, excluding amortization of acquired intangible assets	1,792	1,734	2,432	3,511
Research and development	15,730	12,992	29,348	22,937
Sales and marketing	5,288	6,883	11,025	13,576
General and administrative	9,056	8,557	18,298	17,106
Amortization of acquired intangible assets	0	615	0	1,230
Total operating expenses	31,866	30,781	61,103	58,360
Loss from operations	(22,761)	(19,216)	(44,315)	(37,501)
Other (expense) income:
Interest and other income, net	1,623	362	2,825	423
Interest expense	(435)	(552)	(1,247)	(1,745)
Loss on extinguishment of debt	(1,347)	0	(1,347)	(1,559)
Total other (expense) income, net	(159)	(190)	231	(2,881)
Net loss	$ (22,920)	$ (19,406)	$ (44,084)	$ (40,382)
Net loss per share - basic	$ (0.61)	$ (0.52)	$ (1.17)	$ (1.08)
Net loss per share - diluted	$ (0.61)	$ (0.52)	$ (1.17)	$ (1.08)
Weighted average shares outstanding - basic	37,576	37,322	37,531	37,288
Weighted average shares outstanding - diluted	37,576	37,322	37,531	37,288
Net loss	$ (22,920)	$ (19,406)	$ (44,084)	$ (40,382)
Other comprehensive loss:
Unrealized (loss) gain on available-for-sale securities, net of tax of $0 for periods presented	(1)	(186)	56	(239)
Comprehensive loss	(22,921)	(19,592)	(44,028)	(40,621)
Product [Member]
Revenues:
Total revenues	5,273	11,318	12,667	20,328
License and Collaboration Agreements [Member]
Revenues:
Total revenues	3,597	49	3,631	108
Royalty Income [Member]
Revenues:
Total revenues	$ 235	$ 198	$ 490	$ 423