CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Revenues:
Total revenues	$ 7,683	$ 9,294
Operating expenses:
Cost of sales, excluding amortization of acquired intangible assets	640	1,777
Research and development	13,618	9,945
Sales and marketing	5,737	6,693
General and administrative	9,242	8,548
Amortization of acquired intangible assets	0	615
Total operating expenses	29,237	27,578
Loss from operations	(21,554)	(18,284)
Other income (expense):
Interest and other income, net	1,202	61
Interest expense	(812)	(1,194)
Loss on extinguishment of debt	0	(1,559)
Total other income (expense), net	390	(2,692)
Net loss	$ (21,164)	$ (20,976)
Net loss per share - basic	$ (0.56)	$ (0.56)
Net loss per share - diluted	$ (0.56)	$ (0.56)
Weighted average shares outstanding - basic	37,486	37,253
Weighted average shares outstanding - diluted	37,486	37,253
Net loss	$ (21,164)	$ (20,976)
Other comprehensive loss:
Unrealized gain (loss) on available-for-sale securities, net of tax of $0 for periods presented	57	(53)
Comprehensive loss	(21,107)	(21,029)
Product [Member]
Revenues:
Total revenues	7,394	9,010
License and Collaboration Agreements [Member]
Revenues:
Total revenues	34	59
Royalty Income [Member]
Revenues:
Total revenues	$ 255	$ 225