Income Taxes - Difference Between Expected Income Tax Benefit and Actual Income Tax Benefit (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Tax Disclosure [Abstract]
Income tax benefit at statutory rate	$ (21,473)	$ (12,268)
State income taxes, net of federal benefit	(5,932)	(2,890)
Non-U.S. income tax rate differential	0	0
Change in fair value of derivative	0	0
Change in federal tax rate	0	0
Research and development tax credits	(1,034)	(693)
Permanent items	1,514	729
Changes in valuation allowance	26,083	15,748
Other, net	842	(626)
Income tax expense (benefit)	$ 0	$ 0