Leases - Additional Information (Detail)		12 Months Ended
	Mar. 08, 2022 USD ($) ft²	Dec. 31, 2022 USD ($) ft²	Dec. 31, 2021 USD ($)	Sep. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)
Disclosure Of Leases [Line Items]
Lease liabilities		$ 6,527,000	$ 2,505,000		$ 2,900,000
ROU assets		$ 6,038,000	2,252,000		$ 2,900,000
Operating lease weighted average remaining lease term		5 years 2 months 12 days
Operating lease weighted average discount rate		5.84%
Operating lease expense		$ 1,200,000	885,000
Variable lease cost		63,000	30,000
Operating lease payments		834,000	920,000
Finance lease, amortization expense		133,000	151,000
Interest expense on finance lease liability		12,000	23,000
Finance lease, operating cash flows		12,000	23,000
Finance lease, financing cash flows		$ 137,000	146,000
Finance lease, weighted average Remaining term		6 months
Finance lease, weighted average discount rate, percent		12.50%
Research and Development Expense [Member]
Disclosure Of Leases [Line Items]
Operating lease expense		$ 1,100,000	606,000
Sales and Marketing Expense [Member]
Disclosure Of Leases [Line Items]
Operating lease expense		0	112,000
General and Administrative Expense [Member]
Disclosure Of Leases [Line Items]
Operating lease expense		58,000	$ 167,000
New Premises [Member]
Disclosure Of Leases [Line Items]
Lease liabilities				$ 1,600,000
ROU assets				$ 1,700,000
Massachusetts [Member] | Maximum [Member]
Disclosure Of Leases [Line Items]
Construction allowance		$ 670,750
Massachusetts [Member] | Original Lease [Member]
Disclosure Of Leases [Line Items]
Area of leased office and laboratory space | ft²		13,650
Original lease term		5 years
Lease expiration month year		2019-04
Massachusetts [Member] | Second Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Lease commencement date		Sep. 10, 2018
Lease term expiration date		May 31, 2025
Additional Space leased | ft²		6,590
Irrevocable standby letter of credit		$ 150,000
Massachusetts [Member] | Third Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Area of leased office and laboratory space | ft²		1,409
Lease commencement date		Jul. 01, 2021
Lease term expiration date		May 31, 2025
Massachusetts [Member] | Fourth Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Lease term expiration date	May 31, 2028
Termination of property area | ft²	7,999
Area of leased office space | ft²	13,650
Lease existence of option to extend		true
Additional lease renewal option period	5 years
Massachusetts [Member] | Fourth Amendment Lease [Member] | New Premises [Member]
Disclosure Of Leases [Line Items]
Additional Space leased | ft²	11,999
Massachusetts [Member] | Fourth Amendment Lease [Member] | Maximum [Member]
Disclosure Of Leases [Line Items]
Construction allowance	$ 555,960