CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Income [Member]
Balance at Dec. 31, 2020	$ 18,541	$ 18	$ 528,362	$ (510,680)	$ 841
Balance, shares at Dec. 31, 2020		18,139,981
Net loss	(38,985)			(38,985)
Issuance of stock, net of issue costs	108,414	$ 11	108,403
Issuance of stock, net of issue costs, shares		10,513,538
Employee stock purchase plan	273		273
Employee stock purchase plan, shares		43,365
Exercise of stock options	11		11
Exercise of stock options, shares		1,078
Vesting of stock units	(145)		(145)
Vesting of stock units, shares		73,302
Stock-based compensation	4,639		4,639
Balance at Sep. 30, 2021	92,748	$ 29	641,543	(549,665)	841
Balance, shares at Sep. 30, 2021		28,771,264
Balance at Jun. 30, 2021	106,865	$ 29	638,965	(532,970)	841
Balance, shares at Jun. 30, 2021		28,754,192
Net loss	(16,695)			(16,695)
Issuance of stock, net of issue costs	10		10
Employee stock purchase plan	101		101
Employee stock purchase plan, shares		15,652
Exercise of stock options	1		1
Exercise of stock options, shares		251
Vesting of stock units	(5)		(5)
Vesting of stock units, shares		1,169
Stock-based compensation	2,471		2,471
Balance at Sep. 30, 2021	92,748	$ 29	641,543	(549,665)	841
Balance, shares at Sep. 30, 2021		28,771,264
Balance at Dec. 31, 2021	$ 184,380	$ 34	752,602	(569,097)	841
Balance, shares at Dec. 31, 2021	33,905,826	33,905,826
Net loss	$ (58,802)			(58,802)
Other comprehensive loss	(188)				(188)
Issuance of stock, net of issue costs	20		20
Employee stock purchase plan	354		354
Employee stock purchase plan, shares		47,787
Exercise of stock options	41		41
Exercise of stock options, shares		4,479
Vesting of stock units	(271)		(271)
Vesting of stock units, shares		114,063
Stock-based compensation	10,816		10,816
Balance at Sep. 30, 2022	$ 136,350	$ 34	763,562	(627,899)	653
Balance, shares at Sep. 30, 2022	34,072,155	34,072,155
Balance at Jun. 30, 2022	$ 151,366	$ 34	760,209	(609,479)	602
Balance, shares at Jun. 30, 2022		34,052,616
Net loss	(18,420)			(18,420)
Other comprehensive loss	51				51
Employee stock purchase plan	153		153
Employee stock purchase plan, shares		19,283
Exercise of stock options	1		1
Exercise of stock options, shares		256
Stock-based compensation	3,199		3,199
Balance at Sep. 30, 2022	$ 136,350	$ 34	$ 763,562	$ (627,899)	$ 653
Balance, shares at Sep. 30, 2022	34,072,155	34,072,155