Leases - Additional Information (Detail)		3 Months Ended		9 Months Ended
	Mar. 08, 2022 USD ($) ft² Tranche	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($) ft² Lease	Sep. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Dec. 31, 2021 USD ($)
Disclosure Of Leases [Line Items]
Lease liabilities		$ 6,660,000		$ 6,660,000		$ 2,900,000	$ 2,505,000
ROU assets		$ 6,319,000		$ 6,319,000		$ 2,900,000	$ 2,252,000
Operating lease weighted average remaining lease term		5 years 6 months		5 years 6 months
Operating lease weighted average discount rate		5.89%		5.89%
Operating lease expense		$ 263,000	$ 229,000	$ 781,000	$ 656,000
Variable lease cost		2,000	9,000	8,000	27,000
Operating lease payments		164,000	236,000	595,000	678,000
Finance lease, amortization expense		34,000	46,000	101,000	108,000
Interest expense on finance lease liability		2,000	7,000	11,000	17,000
Finance lease, operating cash flows		3,000	7,000	11,000	17,000
Finance lease, financing cash flows		$ 35,000	$ 45,000	$ 103,000	$ 102,000
Finance lease, weighted average Remaining term		7 months 6 days		7 months 6 days
Finance lease, weighted average discount rate, percent		12.50%		12.50%
Laboratory Equipment [Member]
Disclosure Of Leases [Line Items]
Number of finance leases | Lease				2
First Lab Equipment [Member]
Disclosure Of Leases [Line Items]
Lease expiration month year				2022-12
Second Lab Equipment [Member]
Disclosure Of Leases [Line Items]
Lease expiration month year				2023-06
New Premises [Member]
Disclosure Of Leases [Line Items]
Lease liabilities		$ 1,600,000		$ 1,600,000
ROU assets		1,700,000		1,700,000
Massachusetts [Member] | Maximum [Member]
Disclosure Of Leases [Line Items]
Construction allowance		$ 670,750		$ 670,750
Massachusetts [Member] | Original Lease [Member]
Disclosure Of Leases [Line Items]
Area of leased office and laboratory space | ft²				13,650
Original lease term		5 years		5 years
Lease expiration month year				2019-04
Massachusetts [Member] | Second Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Lease commencement date				Sep. 10, 2018
Lease term expiration date				May 31, 2025
Additional Space leased | ft²				6,590
Irrevocable standby letter of credit		$ 150,000		$ 150,000
Massachusetts [Member] | Third Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Area of leased office and laboratory space | ft²				1,409
Lease commencement date				Jul. 01, 2021
Lease term expiration date				May 31, 2025
Massachusetts [Member] | Fourth Amendment Lease [Member]
Disclosure Of Leases [Line Items]
Area of leased office and laboratory space | ft²	13,650
Lease term expiration date	May 31, 2028
Termination of property area | ft²	7,999
Lease existence of option to extend				true
Number of renewal options | Tranche	1
Additional lease renewal option period	5 years
Massachusetts [Member] | Fourth Amendment Lease [Member] | New Premises [Member]
Disclosure Of Leases [Line Items]
Additional Space leased | ft²	11,999
Massachusetts [Member] | Fourth Amendment Lease [Member] | Maximum [Member]
Disclosure Of Leases [Line Items]
Construction allowance	$ 555,960