X0508 4 2024-08-29 0000859737 HOLOGIC INC HOLX 0001314036 Oberton Karleen Marie 250 CAMPUS DRIVE MARLBOROUGH MA 01752 1 Chief Financial Officer 1 Common Stock 2024-08-29 4 M 0 26080 40.97 A 129996 D Common Stock 2024-08-29 4 M 0 6725 40.85 A 136721 D Common Stock 2024-08-29 4 S 0 52679 80.557 D 84042 D Non-qualified Stock Option (Right to Buy) 40.97 2024-08-29 4 M 0 26080 0 D 2028-11-12 Common Stock 26080 0 D Non-qualified Stock Option (Right to Buy) 40.85 2024-08-29 4 M 0 6725 0 D 2027-12-01 Common Stock 6725 0 D Transaction pursuant to an existing Rule 10b5-1 trading plan adopted on May 30, 2024. Includes 41,121 restricted stock units/performance stock units, the settlement of which has been deferred pursuant to the Issuer's Deferred Equity Plan. The price reported is the weighted average price per share. Shares were sold in multiple transactions at prices ranging from $80.32 to $80.84 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each price. This option to purchase common stock became exercisable in equal installments on each of the first four anniversaries of the grant date, November 12, 2018. This option to purchase common stock became exercisable in equal installments on each of the first four anniversaries of the grant date, December 1, 2017. /s/ Mark W. Irving, attorney-in-fact for Ms. Oberton 2024-09-03