X0303 4 2011-05-13 0000203527 VARIAN MEDICAL SYSTEMS INC VAR 0001313996 WILSON DOW R C/O VARIAN MEDICAL SYSTEMS, INC. 3100 HANSEN WAY, M/S E-327 PALO ALTO CA 94304 1 EVP and Pres. Oncology Sys. Common Stock 2011-05-13 4 M 0 2315 37.17 A 37548 D Common Stock 2011-05-13 4 S 0 1715 69.1597 D 35833 D Common Stock 2011-05-13 4 S 0 600 69.9183 D 35233 D Non Qualified Stock Option (Right to Buy) 37.17 2011-05-13 4 M 0 2315 0 D 2016-02-13 Common Stock 2315 20834 D This transaction is pursuant to the filer's SEC Rule10b5-1 Stock Plan The 1,715 shares were sold in multiple transactions executed on the same day at prices ranging from $68.96 to $69.63. The detailed breakdown of executed sales will be furnished upon request. The 600 shares were sold in multiple transactions executed on the same day at prices ranging from $69.79 to $70.11. The detailed breakdown of executed sales will be furnished upon request. Amount of securities beneficially owned at end of reporting period reflect 584 shares purchased on April 29, 2011 under the Varian Medical Systems, Inc. Employee Stock Purchase Plan. Stock option granted under the Varian Medical Systems, Inc. Second Amended and Restated 2005 Omnibus Stock Plan, which complies with Rule 16b-3. The option vests as follows: one third on 2/13/2010, and the remaining shares in 24 equal installments over the 24 months following the first vesting date. /s/ Franco N. Palomba, Attorney in Fact for Dow R. Wilson 2011-05-16