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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 FXYA1Vzxhp4zaS8L7gSB0w==

<SEC-DOCUMENT>0000899140-07-001506.txt : 20070907
<SEC-HEADER>0000899140-07-001506.hdr.sgml : 20070907
<ACCEPTANCE-DATETIME>20070907182737
ACCESSION NUMBER:		0000899140-07-001506
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070907
FILED AS OF DATE:		20070907
DATE AS OF CHANGE:		20070907

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Macquarie Global Infrastructure Total Return Fund Inc.
		CENTRAL INDEX KEY:			0001326390
		IRS NUMBER:				342045907

	BUSINESS ADDRESS:	
		STREET 1:		C/O MACQUARIE  FUND ADVISER, LLC
		STREET 2:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		212-231-1572

	MAIL ADDRESS:	
		STREET 1:		C/O MACQUARIE  FUND ADVISER, LLC
		STREET 2:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Macquarie Fund Adviser, LLC
		CENTRAL INDEX KEY:			0001313281

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21765
		FILM NUMBER:		071107261

	BUSINESS ADDRESS:	
		STREET 1:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		212-231-1865

	MAIL ADDRESS:	
		STREET 1:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019

	FORMER NAME:	
		FORMER CONFORMED NAME:	Macquarie Infrastructure Fund Adviser, LLC
		DATE OF NAME CHANGE:	20050104
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-09-07</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001326390</issuerCik>
        <issuerName>Macquarie Global Infrastructure Total Return Fund Inc.</issuerName>
        <issuerTradingSymbol>MGU</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001313281</rptOwnerCik>
            <rptOwnerName>Macquarie Fund Adviser, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>125 WEST 55TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Adviser</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Shares</value>
            </securityTitle>
            <transactionDate>
                <value>2007-09-07</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2007-09-07</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>4189</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>29.7219</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Richard C. Butt</signatureName>
        <signatureDate>2007-09-07</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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