Subsequent Event - Additional Information (Detail)		12 Months Ended
	Feb. 17, 2016	Dec. 31, 2015
Subsequent Event [Line Items]
Supply commitment, description		On February 17, 2016, the Company entered into an Agreement for Supply of Materials and Terms of Materials Transfer with Novartis Pharma AG, or Novartis. Under the terms of this agreement, Novartis will provide investigational materials to the Company to be studied in combination with the Company’s CVC in preclinical studies. The Company is responsible for the conduct of the study with all expenses associated with the study to be reimbursed by Novartis, as incurred.
Subsequent Event [Member]
Subsequent Event [Line Items]
Agreement date for supply of materials	Feb. 17, 2016