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Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Detail) - shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total 2,434,504 10,963,063 9,238,212
Convertible Notes [Member]      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total   3,368,650 2,342,727
Common Stock Options [Member]      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total 2,369,847 1,110,744 755,074
Warrant | Common Stock [Member]      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total 64,657    
Warrant | Preferred Stock      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total   901,987 652,937
Convertible Preferred Stock [Member]      
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]      
Total   5,581,682 5,487,474