X0306 4 2014-02-20 0 0001311596 Regado Biosciences Inc RGDO 0001435388 Clark B. Jefferson 120 MOUNTAIN VIEW BOULEVARD C/O REGADO BIOSCIENCES, INC. BASKING RIDGE NJ 07920 1 0 0 0 Common Stock, par value $0.001 per share 2014-02-20 4 X 0 2095 3.34 A 1116854 I See Footnote Common Stock, par value $0.001 per share 2014-02-20 4 X 0 5447 4.51 A 1122301 I See Footnote Common Stock, par value $0.001 per share 2014-02-20 4 X 0 3341 4.51 A 1125642 I See Footnote Common Stock, par value $0.001 per share 2014-02-20 4 X 0 4491 0.17 A 1130133 I See Footnote Stock Option (right to buy) 3.34 2014-02-20 4 X 0 1 0 D 2015-12-20 Common Stock 2095 0 I See Footnote Stock Option (right to buy) 4.51 2014-02-20 4 X 0 1 0 D 2020-04-30 Common Stock 5447 0 I See Footnote Stock Option (right to buy) 4.51 2014-02-20 4 X 0 1 0 D 2020-04-30 Common Stock 3341 0 I See Footnote Warrant (right to buy) 0.17 2014-02-20 4 X 0 1 0 D 2014-02-20 Common Stock 4491 0 I See Footnote The Reporting Person holds the reportable securities as nominee for Aurora Ventures IV, LLC ("Aurora IV"). The Reporting Person is the manager of A.V. Management IV, L.L.C., the managing member of Aurora IV, and may be deemed to share voting and investment power. The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. The Reporting Person holds the reportable securities as nominee for Aurora Ventures V, LP ("Aurora V"). The Reporting Person is the Manager of A.V. Management V, L.L.C., the managing member of Aurora V, and may be deemed to share voting and investment power. The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, and this report is not an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. This option was fully vested and exercisable as of December 20, 2006. This option was fully vested and exercisable as of December 31, 2010. This warrant was exercisable as of November 20, 2004. /s/ B. Jefferson Clark by Christopher Courts, Attorney-in-Fact (power of attorney previously filed) 2014-03-03