X0306 4 2013-12-16 0 0001311596 Regado Biosciences Inc RGDO 0001507220 Metzger Michael A 120 MOUNTAIN VIEW BOULEVARD C/O REGADO BIOSCIENCES, INC. BASKING RIDGE NJ 07920 0 1 0 0 President and COO Stock Option (right to buy) 4.81 2013-12-16 4 A 0 434008 0 A 2023-12-15 Common Stock, par value $0.001 per share 434008 434008 D The option is vested and exercisable as to 108,502 shares. The remaining 325,506 shares underlying the option will vest in 36 equal monthly installments on the fifth day of each calendar month, commencing on January 5, 2014. /s/ Michael A. Metzger 2013-12-20