X0306 4 2013-08-27 0 0001311596 Regado Biosciences Inc RGDO 0001579266 BIODISCOVERY 3, FCPR 47 RUE DU FAUBOURG SAINT HONORE PARIS I0 75401 FRANCE 0 0 1 0 0001579186 Edmond De Rothschild Investment Partners 47 RUE DU FAUBOURG SAINT HONORE PARIS I0 75008 FRANCE 0 0 1 0 Common Stock, par value $0.001 per share 2013-08-27 4 C 0 1021930 A 1021930 D Common Stock, par value $0.001 per share 2013-08-27 4 C 0 169633 A 1191563 D Common Stock, par value $0.001 per share 2013-08-27 4 P 0 1215708 4.00 A 2407271 D Series D Preferred Stock 2013-08-27 4 C 0 17066243 0 D Common Stock, par value $0.001 per share 1021930 0 D Series E Preferred Stock 2013-08-27 4 C 0 2832872 0 D Common Stock, par value $0.001 per share 169633 0 D The reportable securities are directly held by BioDiscovery 3, FCPR ("BioDiscovery"). Edmond de Rothschild Investment Partners, S.A.S. ("Edmond de Rothschild"), as the management company for BioDiscovery indirectly beneficially owns the reportable securities. Raphael Wisniewski is a partner at Edmond de Rothschild and a member of the board of directors of the Issuer. Edmond de Rothschild and Mr. Wisniewski disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest therein, and this report is not an admission that either Edmond de Rothschild or Mr. Wisniewski is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. The shares of Series D Preferred Stock had no expiration date and automatically converted upon the consummation of the initial public offering of Regado Biosciences, Inc. (the "Company") at a conversion ratio of 1 share of Series D Preferred Stock to 0.05988024 shares of common stock, for no additional consideration. The shares of Series E Preferred Stock had no expiration date and automatically converted upon the consummation of the Company's initial public offering at a conversion ratio of 1 share of Series E Preferred Stock to 0.05988024 shares of common stock, for no additional consideration. Edmond de Rothschild Investment Partners, S.A.S, By: /s/ Christopher Courts, Attorney-in-Fact 2013-08-29 BioDiscovery 3, FCPR, By: Edmond de Rothschild By: /s/ Christopher Courts, Attorney-in-Fact 2013-08-29