X0206 3 2013-08-21 0 0001311596 Regado Biosciences Inc RGDO 0001579266 BIODISCOVERY 3, FCPR 47 RUE DU FAUBOURG SAINT HONORE PARIS I0 75401 FRANCE 0 0 1 0 0001579186 Edmond De Rothschild Investment Partners 47 RUE DU FAUBOURG SAINT HONORE PARIS I0 75008 FRANCE 0 0 1 0 Series D Preferred Stock 2009-12-17 Common Stock, par value $0.001 per share 873253 D Series D Preferred Stock 2011-05-25 Common Stock, par value $0.001 per share 148677 D Series E Preferred Stock 2012-12-18 Common Stock, par value $0.001 per share 146060 D Series E Preferred Stock 2013-03-22 Common Stock, par value $0.001 per share 23573 D The shares of Series D Preferred Stock have no expiration date and shall automatically convert upon the consummation of the Issuer's initial public offering at a conversion ratio of 1 share of Series D Preferred Stock to 0.05988024 shares of common stock, for no additional consideration. The reportable securities are directly held by BioDiscovery 3, FCPR ("BioDiscovery"). Edmond de Rothschild Investment Partners, S.A.S. ("Edmond de Rothschild"), as the management company for BioDiscovery indirectly beneficially owns the reportable securities. Raphael Wisniewski is a partner at Edmond de Rothschild and a member of the board of directors of the Issuer. Edmond de Rothschild and Mr. Wisniewski disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest therein, and this report is not an admission that either Edmond de Rothschild or Mr. Wisniewski is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. The shares of Series E Preferred Stock have no expiration date and shall automatically convert upon the consummation of the Issuer's initial public offering at a conversion ratio of 1 share of Series E Preferred Stock to 0.05988024 shares of common stock, for no additional consideration. Edmond de Rothschild Investment Partners, S.A.S. By: /s/ Pierre-Michel Passy, its President 2013-08-21 BioDiscovery 3, FCPR, By: Edmond de Rothschild Investment Partners, S.A.S., its management company, /s/ Pierre-Michel Passy, its President 2013-08-21