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Income Taxes - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Income Tax Contingency        
Income tax provision $ 7,000 $ 8,000 $ 7,000  
Provision for income taxes related to foreign income taxes 6,000 11,000 6,000  
Provision for income taxes related to state minimum income taxes 1,000 1,000 1,000  
Undistributed earnings of foreign subsidiaries 400,000      
Valuation allowance for deferred tax assets 61,766,000 54,420,000    
Increase in valuation allowance 7,400,000 9,400,000    
Unrecognized tax benefits excluding interest 4,212,000 3,757,000 3,261,000 $ 2,656,000
Accrued interest and penalties related to unrecognized tax benefits $ 0 $ 0 $ 0  
Research and Development Expense        
Income Tax Contingency        
Tax credit carryforward, term 20 years      
Internal Revenue Service (IRS)        
Income Tax Contingency        
Deferred tax assets, U.S. net operating loss carryforwards $ 105,500,000      
Adjustments to additional paid in capital, income tax benefit from share-based compensation $ 14,600,000      
Operating loss carryforwards, expiration start year 2026      
Internal Revenue Service (IRS) | Research and Development Expense        
Income Tax Contingency        
Tax credit carryforward $ 10,000,000      
State Jurisdiction        
Income Tax Contingency        
Deferred tax assets, U.S. net operating loss carryforwards 96,600,000      
Adjustments to additional paid in capital, income tax benefit from share-based compensation $ 13,600,000      
Operating loss carryforwards, expiration start year 2018      
State Jurisdiction | Research and Development Expense        
Income Tax Contingency        
Tax credit carryforward $ 11,100,000