Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Revenue:
Program revenue	$ 33,855	$ 30,540	$ 45,744
Product revenue	75	84	6,726
Licensing and royalty revenue	11,392	17,071	14,936
Total revenue	45,322	47,695	67,406
Cost of revenue:
Cost of development program and services revenue	18,910	24,342	29,063
Cost of product revenue	55	16	3,175
Cost of licensing and royalty revenue	339	293	247
Total cost of revenue	19,304	24,651	32,485
Gross profit	26,018	23,044	34,921
Operating expenses:
Research and development	28,576	24,320	24,502
Sales and marketing	5,881	5,770	6,475
General and administrative	12,287	12,636	11,973
Restructuring charges		1,361
Total operating expenses	46,744	44,087	42,950
Loss from operations	(20,726)	(21,043)	(8,029)
Other income (expense):
Interest expense, net	(267)	(682)	(830)
Other income (expense), net	(12)	(29)	57
Total other income (expense), net	(279)	(711)	(773)
Loss before provision for income taxes	(21,005)	(21,754)	(8,802)
Provision for income taxes	8	7	17
Net loss	$ (21,013)	$ (21,761)	$ (8,819)
Net loss per share of common stock, basic and diluted (in dollars per share)	$ (0.44)	$ (0.47)	$ (0.20)
Weighted-average number of shares used in computing net loss per share of common stock, basic and diluted	48,158,378	46,718,495	44,958,120
Related Party Transactions.
Revenue:
Program revenue	$ 35	$ 1,114	$ 7,374
Licensing and royalty revenue	3,279	4,480	5,440
Total revenue	$ 3,314	$ 5,594	$ 12,814