Property, Plant and Equipment-Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property, plant and equipment	$ 46,204	$ 45,404
Less: accumulated depreciation and amortization	(23,530)	(19,408)
Property, plant and equipment - net	22,674	25,996
Plant equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment	25,269	24,824
Building and improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment	5,810	5,810
Lab equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment	7,088	7,495
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment	2,993	1,866
Computer equipment and software
Property, Plant and Equipment [Line Items]
Property, plant and equipment	3,968	3,988
Other
Property, Plant and Equipment [Line Items]
Property, plant and equipment	$ 1,076	$ 1,421