The Company (Details) - USD ($) $ in Thousands		3 Months Ended		9 Months Ended
	Aug. 16, 2016	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015	Aug. 02, 2016	Dec. 31, 2015
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Net loss		$ (20,494)	$ (34,918)	$ (74,444)	$ (106,754)
Accumulated deficit		(684,349)		(684,349)			$ (609,905)
Net cash used in operating activities				(49,501)	$ (69,020)
Cash and cash equivalents and marketable securities		$ 87,800		$ 87,800
Algenist skincare
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Percentage of equity received in disposal	19.90%					19.90%
Total consideration received	$ 20,200
Closing costs	$ 1,400